Texas has one of the broadest ketamine therapy networks in the country, with clinics spread across major metros and smaller communities alike. From the Gulf Coast to the Panhandle, patients can find in-person treatment options without having to travel to a handful of concentrated hubs.
The state's size means the mix of available modalities varies considerably by region. The largest cities offer IV ketamine infusions, Spravato (esketamine), and alternative delivery formats such as intramuscular injections and ketamine-assisted psychotherapy, while many mid-size cities and suburbs have at least one clinic offering one or more of these approaches.
This directory focuses exclusively on clinics that administer ketamine therapy in person, on site. Whether you are exploring options in a major metro or a smaller city, the listings below can help you identify providers, compare modalities, and ask the right questions before scheduling a consultation.
Ketamine Clinics by City in Texas
Allen
2 clinics
Amarillo
1 clinic
Argyle
1 clinic
Arlington
1 clinic
Austin
18 clinics
Beaumont
1 clinic
Bee Cave
1 clinic
Bellaire
3 clinics
Bridge City
1 clinic
Brownsville
2 clinics
Cedar Park
1 clinic
College Station
1 clinic
Columbus
1 clinic
Conroe
1 clinic
Corpus Christi
1 clinic
Cypress
2 clinics
Dallas
10 clinics
Denton
1 clinic
Dripping Springs
2 clinics
Edinburg
1 clinic
El Paso
4 clinics
Farmers Branch
1 clinic
Flint
1 clinic
Flower Mound
2 clinics
Fort Worth
6 clinics
Frisco
7 clinics
Garland
1 clinic
Georgetown
1 clinic
Harker Heights
1 clinic
Harlingen
1 clinic
Houston
20 clinics
Irving
1 clinic
Katy
2 clinics
Killeen
1 clinic
Kingwood
1 clinic
Lakeway
1 clinic
Laredo
1 clinic
Leander
1 clinic
Longview
1 clinic
McKinney
7 clinics
Mesquite
1 clinic
Midland
1 clinic
Nederland
1 clinic
Plano
2 clinics
Richardson
1 clinic
Richmond
1 clinic
Rockwall
2 clinics
Rosenberg
1 clinic
Round Rock
1 clinic
San Antonio
11 clinics
Shenandoah
1 clinic
Southlake
4 clinics
Spring
1 clinic
Stafford
1 clinic
Sugar Land
4 clinics
Texarkana
1 clinic
The Woodlands
1 clinic
Tomball
1 clinic
Trophy Club
1 clinic
Tyler
1 clinic
Waco
1 clinic
Weatherford
1 clinic
West Lake Hills
1 clinic
Where to Find Ketamine Therapy in Texas
Houston
20 clinicsHouston anchors ketamine care for the Gulf Coast region and carries one of the widest selections of modalities in the state, including IV infusions, Spravato, and several forms of ketamine-assisted therapy. The metro also extends into surrounding communities like Sugar Land, The Woodlands, Cypress, Kingwood, and Katy, giving patients meaningful geographic flexibility. Clinics here range from standalone infusion centers to psychiatric practices that integrate ketamine into broader mental health treatment plans.
Austin
18 clinicsAustin and its surrounding Hill Country suburbs represent one of the densest concentrations of ketamine providers in Texas, with IV infusion, Spravato, and therapy-integrated formats all available within the metro. Communities like Cedar Park, Round Rock, Leander, Bee Cave, West Lake Hills, and Dripping Springs extend access well beyond the city core. The area's growth has attracted a variety of practice models, making it worth comparing clinic philosophies as well as modalities when researching options here.
San Antonio
11 clinicsSan Antonio supports a solid range of ketamine services, including IV infusions, Spravato, and therapy-integrated approaches, serving both city residents and patients from surrounding South Texas communities. The clinic landscape here tends to blend psychiatric practices with dedicated infusion providers. Its central location within the state also makes it a practical destination for patients traveling from less-served areas nearby.
Dallas
10 clinicsDallas sits at the center of a large cluster of North Texas clinics, with IV infusions, Spravato, and a variety of ketamine therapy formats available across the city and its suburbs, including Farmers Branch, Arlington, Fort Worth, Southlake, Rockwall, and McKinney. The breadth of providers in this metro means patients can often find specialists aligned with their specific diagnosis or preferred treatment approach. Comparing integration of therapy support and monitoring protocols is especially worthwhile given the number of options.
- Serenity Mental Health Centers
Dallas
IV Ketamine InfusionSpravato (Esketamine)TMSMedication Management
Frisco
7 clinicsFrisco has emerged as a notable destination for ketamine care in the northern Dallas-Fort Worth corridor, offering IV infusions, Spravato, and therapy-based formats within a single suburb. Its proximity to McKinney, Trophy Club, and other fast-growing communities positions it as a convenient access point for patients across that part of the metroplex. Clinics in Frisco tend to reflect the suburb's newer healthcare infrastructure, with several practices offering multiple modalities under one roof.
- Serenity Mental Health Centers
Frisco
IV Ketamine InfusionSpravato (Esketamine)TMSPsychiatryMedication Management
How Much Ketamine Therapy Costs in Texas
Across 16 clinics that publish rates, in-person sessions run $125 to $1,350 per session. A standard starter course of six sessions works out to roughly $2,628 based on the median published price. Many clinics offer package or self-pay options, so confirm current pricing directly with the provider.
Several Texas clinics publish their per-session or per-course pricing, which makes it easier to do a rough comparison before booking a consultation. That said, published rates are not universal across all providers, and the final cost often depends on factors like the modality chosen, the number of sessions in a recommended course, whether any preparatory medical evaluations are required, and what kind of integration support is included. IV infusion protocols typically involve a series of sessions rather than a single visit, so the full course price is the more meaningful figure to ask about. Spravato, the FDA-approved nasal-spray form of esketamine, is administered in certified clinical settings and may be covered by insurance for patients who meet specific diagnostic criteria, which can substantially affect out-of-pocket cost compared to IV ketamine. Therapy-integrated approaches that pair ketamine with psychotherapy sessions may carry additional fees depending on the provider's model. Asking upfront about what is and is not included in a quoted price is one of the most practical steps you can take during a clinic consultation.
Types of Ketamine Treatment Offered in Texas
Texas clinics offer three main modalities: IV ketamine infusions, Spravato (esketamine nasal spray), and broader ketamine therapy approaches that may include intramuscular injections, sublingual formulations, or ketamine-assisted psychotherapy. IV infusion is available across a wide swath of the state, including Houston, Austin, Dallas, San Antonio, Frisco, Fort Worth, El Paso, The Woodlands, Sugar Land, Southlake, Rockwall, McKinney, Arlington, Beaumont, Farmers Branch, Texarkana, and Trophy Club. Spravato has an even broader footprint, reaching not only those cities but also Amarillo, Brownsville, College Station, Corpus-adjacent areas, Cypress, Denton, Edinburg, Harlingen, Katy, Killeen, Laredo, Leander, Longview, and more. Spravato is an FDA-approved medication dispensed only in certified healthcare settings under a federal monitoring program, so patients receive and recover from each dose on site. The therapy-integrated category, which covers IM, sublingual, and KAP formats, has the widest geographic reach of all, extending to communities like Waco, Tyler, Midland, Corpus Christi, Round Rock, Plano, Richardson, Georgetown, Garland, Flower Mound, Weatherford, and many others. This directory lists only clinics that provide in-person, on-site administration, so every provider you find here requires a physical visit for treatment.
- IV Ketamine Infusion offered at 29 clinics, including Arlington, Austin, Beaumont, Dallas.
- Spravato (Esketamine) offered at 66 clinics, including Amarillo, Arlington, Austin, Beaumont.
- Ketamine Therapy offered at 97 clinics, including Allen, Argyle, Austin, Beaumont.
How to Choose a Ketamine Clinic in Texas
Because Texas has clinics spread across both dense metros and smaller cities, the best starting point is narrowing your search by geography first, then comparing modalities within a reasonable distance. Here is a practical framework: Start by identifying which cities near you have the modality your provider recommended, since IV infusion, Spravato, and therapy-integrated options are not uniformly available everywhere. Ask each clinic whether they offer a full course of treatment or only single sessions, because for most protocols a complete course matters more than any one visit. Confirm that a licensed medical professional will conduct an intake evaluation before treatment begins. For Spravato specifically, verify the clinic holds the required federal certification and that monitoring is done on site. If you are interested in ketamine-assisted psychotherapy, ask whether a licensed therapist is involved in sessions or available for integration support afterward. In the major metros, you will often have enough options to compare clinic philosophies, staff credentials, and patient-to-provider ratios. In smaller cities, the question is more often whether the available modality matches your clinical needs and whether the provider has experience with your specific diagnosis. Always request a consultation before committing to a full course.
Ketamine Therapy in Texas: Frequently Asked Questions
What conditions is ketamine therapy commonly used for?
Ketamine therapy is used by licensed providers as a treatment approach for conditions including treatment-resistant depression, major depressive disorder, post-traumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and certain chronic pain conditions. It is not a first-line or standalone cure, and whether it is appropriate for you depends on a clinical evaluation. A licensed medical provider at a Texas clinic can assess your history and discuss whether ketamine therapy fits your situation.
What is the difference between IV ketamine infusions and Spravato?
IV ketamine is administered intravenously in a clinic setting and involves a series of infusion sessions, typically over a few weeks. It is used off-label, meaning it is not FDA-approved for a specific psychiatric indication but is legally prescribed by licensed clinicians for that purpose. Spravato is a nasal spray form of esketamine that is FDA-approved for treatment-resistant depression and major depressive disorder with suicidal ideation. Because of a federal monitoring requirement, Spravato must be taken in a certified healthcare setting and patients stay on site for observation afterward. Both are available at clinics across Texas, though the two approaches differ in administration, monitoring requirements, and potential insurance coverage.
What does a typical ketamine therapy visit in Texas look like?
Most patients begin with a medical intake or consultation to review their history, current medications, and treatment goals. For IV infusions, you arrive at the clinic, are set up with an IV line, and receive the infusion in a monitored room over a period of time determined by the protocol. For Spravato, you self-administer the nasal spray under clinical supervision and remain at the clinic for observation. Therapy-integrated approaches may involve a preparation session before the ketamine experience and an integration session afterward to process what came up. You should plan for someone else to drive you home regardless of the modality.
Does insurance cover ketamine therapy in Texas?
Coverage varies depending on the modality and your specific plan. Spravato is the only FDA-approved form and is the most likely to be covered by insurance for patients who meet the clinical criteria, though prior authorization is commonly required. IV ketamine infusions are typically paid out of pocket because they are used off-label, and most health plans do not reimburse them. Some patients use health savings accounts or financing options offered by clinics. Asking a clinic directly about their payment process and whether they can assist with insurance verification is the most reliable way to understand your costs.
How much does a course of ketamine treatment cost in Texas?
Several Texas clinics publish their pricing, and a starter course will represent a meaningful financial commitment. The total depends on the modality, how many sessions are included, any required medical evaluations, and whether therapy support is bundled in. Spravato may carry a different cost profile than IV infusions because of potential insurance coverage. Asking for an itemized estimate that covers the full recommended course, not just a single session, gives you the most accurate picture before committing.
Which cities in Texas have ketamine clinics?
Texas has one of the most geographically distributed ketamine clinic networks in the country. The largest concentrations are in Houston, Dallas, Austin, San Antonio, and Frisco, but clinics also operate in mid-size cities and suburbs such as Fort Worth, El Paso, McKinney, The Woodlands, Sugar Land, Beaumont, Amarillo, Corpus Christi, Waco, Tyler, Midland, Laredo, and many others. Smaller communities including Round Rock, Georgetown, Leander, Denton, Southlake, and Rockwall, among others, also have at least one provider. You can search this directory by city to see what is available near you.
Is ketamine therapy only available in the big Texas metros?
No. While Houston, Dallas, and Austin have the most clinic options, ketamine therapy, particularly Spravato, reaches a broad range of Texas communities, including smaller cities along the Gulf Coast, border communities, East Texas, West Texas, and Central Texas. IV infusions are also available outside the major metros, with clinics in cities like Beaumont, Texarkana, and El Paso. If you live in a rural area without a nearby provider, it may be worth traveling to a closer regional hub for an initial consultation.
Are the clinics listed here telehealth or in-person?
Every clinic listed in this directory provides treatment in person, at a physical clinic location. Ketamine must be administered on site by or under the supervision of a licensed medical professional, and this directory reflects that requirement. You will need to attend sessions at the clinic, not at home.
How do I choose between the different ketamine modalities?
The right modality depends on your diagnosis, medical history, and what a qualified provider recommends after evaluating you. IV infusions are well-established and widely available across Texas. Spravato is FDA-approved for specific diagnoses and may be covered by insurance. Therapy-integrated formats are often preferred when patients or providers want psychological support woven into the treatment. A consultation with a licensed clinician is the appropriate first step before deciding on a modality.
What questions should I ask a Texas ketamine clinic before booking treatment?
Ask about the credentials of the clinician who will supervise your sessions, what the intake process involves, how many sessions are included in their recommended protocol, what monitoring happens during and after treatment, and whether integration support is available. For Spravato, confirm the clinic holds the required federal certification. For IV infusions, ask about the setting, who is present during the infusion, and what happens if you have a difficult reaction. Getting clarity on total cost upfront, including any consultation fees, is also important before committing.
Is ketamine therapy legal in Texas?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions. Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Texas as it does nationwide. The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in Texas and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.