Ketamine Therapy Clinics in California
352 in-person clinics across 148 cities in California.
California hosts one of the most expansive networks of ketamine therapy clinics in the country, stretching from the Oregon border down to San Diego and from the coast into the Central Valley and Inland Empire. Whether you are in a major metro or a smaller community like Chico, Stockton, or Arroyo Grande, there is a good chance a licensed clinic operates within a reasonable drive.
The breadth of California's clinic landscape means patients have real options when it comes to modalities. IV infusion, Spravato (esketamine), and broader ketamine therapy approaches that include intramuscular, sublingual, and ketamine-assisted psychotherapy formats are all represented across the state. Major population centers tend to have the widest variety, but Spravato in particular has made its way into a striking number of mid-size cities and suburban communities.
This directory focuses exclusively on clinics that administer treatment in person at a physical location. If you are beginning your search, the sections below will help you understand what is available, what shapes pricing, and how to evaluate your options.
Ketamine Clinics by City in California
Agoura Hills
2 clinics
Anaheim
1 clinic
Arroyo Grande
2 clinics
Auburn
1 clinic
Bakersfield
6 clinics
Berkeley
4 clinics
Beverly Hills
3 clinics
Brea
1 clinic
Burbank
1 clinic
Burlingame
2 clinics
California City
1 clinic
Camarillo
1 clinic
Campbell
1 clinic
Canyon Country
1 clinic
Capitola
1 clinic
Cardiff
1 clinic
Carlsbad
2 clinics
Castro Valley
1 clinic
Chico
3 clinics
Chino
1 clinic
Chula Vista
2 clinics
Claremont
1 clinic
Concord
3 clinics
Corona
4 clinics
Corte Madera
3 clinics
Costa Mesa
2 clinics
Covina
1 clinic
Culver City
1 clinic
Cypress
1 clinic
Danville
1 clinic
Davis
1 clinic
Del Mar
1 clinic
Downey
1 clinic
Eastvale
1 clinic
El Cajon
2 clinics
El Centro
1 clinic
El Dorado Hills
1 clinic
Elk Grove
2 clinics
Emeryville
1 clinic
Encinitas
3 clinics
Encino
4 clinics
Eureka
1 clinic
Fairfax
1 clinic
Fairfield
2 clinics
Fair Oaks
1 clinic
Folsom
5 clinics
Fremont
2 clinics
Fresno
6 clinics
Galt
1 clinic
Garden Grove
1 clinic
Glendora
1 clinic
Healdsburg
1 clinic
Hemet
1 clinic
Hermosa Beach
1 clinic
Hesperia
1 clinic
Huntington Beach
3 clinics
Indio
1 clinic
Irvine
6 clinics
Laguna Beach
1 clinic
Laguna Hills
3 clinics
La Jolla
5 clinics
Lake Elsinore
1 clinic
Lake Forest
3 clinics
Lancaster
1 clinic
Livermore
1 clinic
Loma Linda
1 clinic
Long Beach
6 clinics
Los Alamitos
1 clinic
Los Altos
1 clinic
Los Angeles
14 clinics
Los Gatos
1 clinic
Malibu
1 clinic
Manhattan Beach
3 clinics
Marina del Rey
2 clinics
Menlo Park
2 clinics
Merced
1 clinic
Milpitas
1 clinic
Mission Viejo
1 clinic
Modesto
2 clinics
Monterey
1 clinic
Moreno Valley
1 clinic
Newhall
1 clinic
Newport Beach
7 clinics
Norco
1 clinic
Oakland
8 clinics
Ojai
1 clinic
Orange
1 clinic
Oxnard
1 clinic
Palm Desert
4 clinics
Palm Springs
1 clinic
Palo Alto
1 clinic
Pasadena
7 clinics
Pittsburg
1 clinic
Pleasant Hill
1 clinic
Pleasanton
1 clinic
Rancho Cucamonga
2 clinics
Red Bluff
1 clinic
Redding
6 clinics
Redlands
2 clinics
Redondo Beach
2 clinics
Redwood City
1 clinic
Riverside
4 clinics
Rocklin
2 clinics
Roseville
8 clinics
Sacramento
10 clinics
Salinas
1 clinic
San Anselmo
1 clinic
San Bernardino
2 clinics
San Diego
14 clinics
San Francisco
14 clinics
San Jose
7 clinics
San Juan Capistrano
2 clinics
San Luis Obispo
2 clinics
San Marcos
1 clinic
San Mateo
2 clinics
San Rafael
3 clinics
Santa Barbara
5 clinics
Santa Clarita
1 clinic
Santa Monica
7 clinics
Santa Rosa
2 clinics
Seal Beach
1 clinic
Sherman Oaks
1 clinic
Solana Beach
1 clinic
South Lake Tahoe
1 clinic
Stockton
2 clinics
Sunnyvale
2 clinics
Tarzana
1 clinic
Temecula
5 clinics
Thousand Oaks
3 clinics
Toluca Lake
2 clinics
Torrance
5 clinics
Tustin
2 clinics
Upland
3 clinics
Vacaville
1 clinic
Valencia
1 clinic
Ventura
2 clinics
Victorville
1 clinic
Visalia
1 clinic
Walnut Creek
3 clinics
West Covina
1 clinic
West Hollywood
3 clinics
Westlake Village
4 clinics
Wildomar
1 clinic
Windsor
1 clinic
Woodland Hills
1 clinic
Yuba City
1 clinic
Yucaipa
1 clinic
Yucca Valley
1 clinic
Where to Find Ketamine Therapy in California
Los Angeles
14 clinicsLos Angeles anchors the state's largest concentration of ketamine clinics, with providers spread across neighborhoods and surrounding communities including Beverly Hills, Santa Monica, West Hollywood, Culver City, and Pasadena. All three major modalities are well represented here, giving patients meaningful choices between IV infusion, Spravato, and integrative ketamine therapy approaches. The sheer density of the metro means that competition among providers is real, and many LA-area clinics publish transparent per-session pricing.
- Mindful Health Solutions
Los Angeles
IV Ketamine InfusionSpravato (Esketamine)TMSPsychiatryMedication ManagementTherapy
San Diego
14 clinicsSan Diego's clinic scene extends well beyond the city itself, reaching coastal communities like La Jolla, Encinitas, and Carlsbad as well as inland areas such as El Cajon, Chula Vista, and Temecula. IV infusion and Spravato are both accessible in the region, and ketamine-assisted psychotherapy is available at several practices that emphasize an integrative, psychology-informed model. The region's military and veteran population has contributed to notable provider interest in treatment-resistant depression and PTSD applications.
- Aloha Integrative Health
San Diego
IV Ketamine InfusionKetamine TherapySpravato (Esketamine)TMSPsychiatry - LifeStance Health
San Diego
IV Ketamine InfusionSpravato (Esketamine)PsychiatryMedication ManagementTherapy
San Francisco
14 clinicsSan Francisco serves as the northern anchor of a densely connected Bay Area clinic network that also spans Oakland, Emeryville, Burlingame, Corte Madera, and Menlo Park. IV ketamine infusion and Spravato are both offered within the city, and ketamine therapy in integrative formats is accessible across the wider metro. The Bay Area's culture of wellness and mental health openness has fostered clinics that often pair ketamine treatment with preparatory and integration therapy sessions.
- LifeStance Health
San Francisco
IV Ketamine InfusionSpravato (Esketamine)PsychiatryMedication ManagementTherapy - Mindful Health Solutions
San Francisco
IV Ketamine InfusionSpravato (Esketamine)TMSPsychiatryMedication ManagementTherapy
Sacramento
10 clinicsSacramento functions as the hub for the northern Central Valley and nearby foothills, with additional clinics operating in Roseville, Rocklin, El Dorado Hills, Fair Oaks, and Folsom. IV infusion and Spravato are available in the region, as are broader ketamine therapy formats, making Sacramento a genuinely multi-modal market. Patients in communities like Chico, Redding, and Stockton who lack a local clinic of their preferred type may find Sacramento the most practical destination.
- Mindful Health Solutions
Sacramento
IV Ketamine InfusionSpravato (Esketamine)TMSPsychiatryMedication ManagementTherapy - Neuro Wellness Spa
Sacramento
IV Ketamine InfusionSpravato (Esketamine)TMSMedication ManagementTherapy
Oakland
8 clinicsOakland offers its own cluster of clinics independent of San Francisco, with IV infusion, Spravato, and ketamine therapy all accessible within the city. Its East Bay location makes it a practical option for patients coming from Concord, Walnut Creek, Pleasanton, and other inland communities. Several Oakland providers take a therapy-integrated approach, pairing the clinical administration of ketamine with structured psychological support.
- Mindful Health Solutions
Oakland
IV Ketamine InfusionSpravato (Esketamine)TMSPsychiatryMedication ManagementTherapy
How Much Ketamine Therapy Costs in California
Across 32 clinics that publish rates, in-person sessions run $150 to $2,000 per session. A standard starter course of six sessions works out to roughly $3,450 based on the median published price. Many clinics offer package or self-pay options, so confirm current pricing directly with the provider.
California is one of the states where published per-infusion pricing is genuinely available from a meaningful sample of clinics, so comparison shopping is possible to a degree not always seen elsewhere. That said, price varies considerably based on the modality chosen, the format of care, and the geographic market. IV infusion courses, which typically involve multiple sessions spread over a few weeks, tend to represent the largest upfront investment. Spravato, being FDA-approved, may be covered by insurance under certain conditions at certified provider locations, which can meaningfully shift the out-of-pocket picture. Clinics that layer in preparatory or integration therapy sessions, integration coaching, or anesthesiologist oversight generally charge more than those offering a more clinical-only model. Clinics in high-cost markets like Beverly Hills, Malibu, and San Francisco's city core often reflect local overhead in their rates. Patients in the Central Valley or Inland Empire may find pricing somewhat more accessible. Regardless of location, it is worth asking each clinic directly about package pricing, single-session options, and whether any financing or sliding-scale arrangements are available.
Types of Ketamine Treatment Offered in California
Three modalities appear throughout California's clinic directory: IV ketamine infusion, Spravato (esketamine), and a broader category of ketamine therapy that includes intramuscular injection, sublingual administration, and ketamine-assisted psychotherapy. IV infusion is the most geographically widespread, available in dozens of communities from Redding and Chico in the north through the Bay Area, the Central Valley, Greater Los Angeles, and down to San Diego's coastal and inland suburbs. Spravato has an especially broad footprint in California, appearing in a remarkably large number of cities including many mid-size communities like Modesto, Visalia, Merced, Riverside, and Palm Desert where IV-only options may be more limited. Spravato is an FDA-approved nasal spray form of esketamine dispensed only in certified clinical settings under a federal safety program, so patients must remain on-site for observation after each dose. The broader ketamine therapy category, which often incorporates a psychotherapeutic framework around the medication session, is concentrated in the Bay Area, Greater Los Angeles, and coastal San Diego communities like La Jolla, Del Mar, Encinitas, and Solana Beach, though it also appears in inland areas. This directory lists only clinics that provide in-person treatment at a licensed facility, so every listing you find here reflects an actual physical location where care is administered.
- IV Ketamine Infusion offered at 81 clinics, including Arroyo Grande, Bakersfield, Beverly Hills, Brea.
- Spravato (Esketamine) offered at 202 clinics, including Agoura Hills, Anaheim, Arroyo Grande, Auburn.
- Ketamine Therapy offered at 168 clinics, including Agoura Hills, Arroyo Grande, Bakersfield, Berkeley.
How to Choose a Ketamine Clinic in California
California's clinic landscape is unusually large and varied, which is an advantage but can also make the search feel overwhelming. A few practical considerations can narrow the field quickly. Start with geography: the state is enormous, and travel time matters for a treatment course that typically requires multiple visits over several weeks. If you are in a smaller city, check whether a nearby regional hub like Sacramento, Fresno, or the Inland Empire's Riverside-San Bernardino area has the modality you need before committing to a long-distance option. Next, clarify modality: if your prescribing physician has recommended Spravato specifically, confirm the clinic is a certified provider; if you are interested in a therapy-integrated approach, ask explicitly how the clinic structures its sessions and whether a licensed therapist is involved. Credential-check the clinical team, looking for board-certified anesthesiologists, psychiatrists, or other licensed providers with documented ketamine experience. Ask about the intake process: a reputable clinic will want your medical history and should conduct a formal evaluation before recommending a treatment path. Since published pricing exists for many California clinics, compare costs directly, and ask whether the quoted price includes monitoring, follow-up, and any integration support. Finally, for Spravato specifically, ask upfront about insurance verification, since FDA approval creates a pathway to coverage that does not exist for IV infusion.
Ketamine Therapy in California: Frequently Asked Questions
What conditions is ketamine therapy used for in California clinics?
California clinics commonly offer ketamine therapy for adults experiencing treatment-resistant depression, major depressive disorder, post-traumatic stress disorder, anxiety disorders, obsessive-compulsive disorder, and certain chronic pain conditions. Some clinics with a psychotherapy integration focus also work with patients seeking to address grief, trauma, or existential distress. Whether ketamine therapy is appropriate for your specific situation is a determination a licensed medical provider must make after a thorough evaluation.
What is the difference between IV ketamine infusion and Spravato?
IV ketamine infusion delivers the medication directly into a vein at a carefully controlled rate and is administered off-label based on decades of clinical use. Spravato is a nasal spray containing esketamine, a closely related compound, and is the only FDA-approved ketamine-based treatment for treatment-resistant depression and depressive symptoms in adults with suicidal ideation. Spravato is dispensed exclusively in certified healthcare settings under a federal safety program that requires patients to be observed on-site for at least two hours after each dose. Both are available from multiple California providers, though Spravato has an especially wide geographic reach across the state.
What does a typical ketamine therapy visit involve?
Before your first session, most clinics will conduct a medical intake that includes reviewing your psychiatric and medical history, current medications, and treatment goals. On the day of an IV infusion, you will typically spend between forty-five minutes and a couple of hours in a reclined position while the medication is administered and clinical staff monitor your vital signs. Spravato sessions involve self-administering the nasal spray under supervision and then remaining at the clinic for an observation period. Some clinics, particularly those offering ketamine-assisted psychotherapy, also provide preparatory sessions before treatment and integration sessions afterward to help you process the experience.
How many sessions will I need?
Most protocols for conditions like treatment-resistant depression begin with a series of infusions or Spravato sessions, often structured over a few weeks, followed by a reassessment of response. The exact number varies by modality, individual response, and the clinical judgment of the treating provider. A starting course for IV infusion typically involves several sessions rather than just one, and Spravato protocols are usually ongoing rather than time-limited. Your treating clinician will outline a recommended schedule based on your specific situation.
Which California cities have ketamine clinics?
Clinics are spread across a large number of California communities. The greatest concentration is in and around Los Angeles, the Bay Area, and San Diego, but providers also operate throughout the Central Valley, the Inland Empire, the Sacramento region, and communities along the Central Coast. Mid-size cities like Fresno, Bakersfield, Modesto, Riverside, and Stockton have options, as do smaller coastal and foothill towns. The city pages on this directory list what is available locally and can help you identify the nearest provider to your area.
Will insurance cover ketamine therapy in California?
Coverage varies widely. IV ketamine infusion is administered off-label and is generally not covered by standard health insurance plans, meaning most patients pay out of pocket. Spravato has a more defined coverage pathway because of its FDA approval, and some insurance plans, including certain Medicaid and Medicare plans, do cover it at certified clinic locations. Verification of your specific plan's benefits is essential before scheduling. Many clinics in California offer financing options or multi-session package pricing to help manage costs.
How much does ketamine therapy cost in California?
California is one of the states where per-infusion pricing is published by a meaningful number of clinics, so some direct comparison is possible. Costs are shaped by the modality, the clinical team's credentials, the level of integration support offered, and the local market. High-demand coastal markets like Beverly Hills, Malibu, and San Francisco tend to reflect higher overhead in their rates, while Central Valley and Inland Empire providers may be more affordable. A typical initial course of IV infusions represents a multi-session investment, and patients should ask each clinic about full course pricing, single-session rates, and available financing before committing.
Is ketamine-assisted psychotherapy different from an IV infusion clinic?
Yes, in meaningful ways. A ketamine-assisted psychotherapy clinic pairs the medication session with structured psychological support, usually involving preparation sessions before the ketamine experience and integration sessions afterward facilitated by a licensed therapist. The goal is to use the medication's effects to support deeper therapeutic work. Standard IV infusion clinics focus primarily on the physiological effects of the drug itself, without a formal psychotherapy component. Both approaches are represented in California, with KAP-oriented practices particularly common in the Bay Area and coastal Southern California communities.
Does this directory include at-home or telehealth ketamine services?
No. Every listing in this directory represents a clinic that administers ketamine treatment in person at a physical location. At-home and telehealth ketamine services are not included.
How do I choose between the many clinics available in a large California metro?
Start by confirming the clinic offers the modality your provider has recommended. Then review the clinical team's credentials, specifically looking for licensed physicians with documented ketamine experience such as board-certified psychiatrists or anesthesiologists. Ask about the intake process: a thorough evaluation before treatment is a positive sign. Compare published pricing directly, and ask what is included in the quoted cost. Finally, consider logistics: parking, accessibility, and whether the clinic's scheduling works for a multi-week treatment course. Reading verified patient reviews and asking for a consultation call before committing can also reveal a great deal about how a clinic operates.
Is ketamine therapy legal in California?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions. Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in California as it does nationwide. The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in California and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.