Ketamine Therapy Clinics in Tennessee
Tennessee has a broad spread of in-person ketamine therapy clinics, with the heaviest concentration around Nashville and its suburbs but real options stretching east to Knoxville and into smaller communities across the state. This page pulls together what is available so you can compare cities, treatment formats, and published pricing in one place.
Ketamine therapy is used for conditions that have not responded well to other treatments. These include treatment-resistant depression, PTSD, OCD, certain anxiety disorders, and some chronic pain conditions. Whether it is a reasonable option for you depends on your specific history, so a licensed medical provider should make that call.
Every listing in this directory is an in-person clinic where treatment is administered on site. You will find clinics offering IV infusion, the FDA-approved nasal spray Spravato, and other formats across Tennessee, with the mix varying by city.
Where to Find Ketamine Therapy in Tennessee
Clinics are spread across both ends of the state, with the densest activity in the Nashville metro area and a solid cluster in and around Knoxville. Smaller cities from Clarksville and Murfreesboro to Johnson City and Jackson also have options worth checking.
Nashville
16 clinicsNashville, Tennessee's capital along the Cumberland River, is one of the busier areas in the state for ketamine therapy.
Providers here offer IV infusion, IM ketamine, and Spravato, drawing patients from across Middle Tennessee's surrounding counties and smaller towns. The concentration of options makes it a practical hub for people coming in from well beyond the city limits.
View all 16 clinics in NashvilleFranklin
8 clinicsFranklin, about 20 miles south of downtown Nashville in Williamson County, is one of the busier areas in the state for ketamine care.
Clinics here offer IV infusion, IM ketamine, and Spravato to patients across the residential corridor stretching through Brentwood and toward Spring Hill. Its position at the southern edge of the Nashville metro makes it convenient for much of Williamson County.
View all 8 clinics in FranklinKnoxville
8 clinicsKnoxville sits along the Tennessee River near the foothills of the Great Smoky Mountains, serving as the main hub for ketamine therapy across East Tennessee.
Providers here offer IV infusion, IM ketamine, and Spravato, drawing patients from the region's surrounding counties. As the largest city in eastern Tennessee, it covers a wide geographic reach that smaller nearby communities depend on.
View all 8 clinics in KnoxvilleCordova
6 clinicsCordova is a suburban community on the eastern edge of Memphis in Shelby County, and it hosts one of the busier concentrations of Spravato access in the state.
Residents from eastern Shelby County and neighboring communities find it a practical alternative to traveling deeper into Memphis proper. Spravato is the format available here, administered in a supervised clinical setting.
View all 6 clinics in CordovaMurfreesboro
5 clinicsMurfreesboro, about 35 miles southeast of Nashville, has grown into a regional center for Rutherford County and draws patients from the broader south-central fringe of the metro.
Several providers here offer Spravato and IM ketamine for people who prefer not to travel all the way into Nashville. Its rapid population growth has made ketamine access here more substantial than many comparably sized Tennessee cities.
View all 5 clinics in MurfreesboroBrentwood
4 clinicsBrentwood borders Nashville to the south in Williamson County and is a well-established destination for southern-suburb residents seeking ketamine therapy. Several providers offer IV infusion and Spravato, serving people who live throughout the Nashville metro's southern tier.
Its close proximity to Nashville means patients get a quieter suburban setting without losing access to a solid range of treatment formats.
View all 4 clinics in BrentwoodMore Cities in Tennessee
Ketamine and Spravato providers also operate in these Tennessee cities. Select one to see local clinics, treatment formats, and how to get started.
Arlington
1 clinic
Bartlett
1 clinic
Bristol
2 clinics
Chattanooga
4 clinics
Clarksville
3 clinics
Cleveland
1 clinic
Collierville
1 clinic
Crossville
1 clinic
Dickson
1 clinic
Dyersburg
1 clinic
Gallatin
1 clinic
Germantown
1 clinic
Goodlettsville
1 clinic
Hendersonville
1 clinic
Hixson
1 clinic
Jackson
4 clinics
Johnson City
4 clinics
Kingsport
2 clinics
Lebanon
2 clinics
Lenoir City
1 clinic
Lexington
1 clinic
Maryville
2 clinics
McMinnville
1 clinic
Memphis
3 clinics
Mount Juliet
2 clinics
Ooltewah
1 clinic
Union City
1 clinic
How Much Ketamine Therapy Costs in Tennessee
Ketamine infusion cost in Tennessee: $150 to $1,200 per session, with a median of $350 (based on 9 clinics with published pricing).
A number of Tennessee clinics publish their per-infusion pricing, which gives you a reasonable starting point for comparison, though many others do not list rates publicly and require a direct call. What you pay will depend on which treatment you choose and how many sessions your provider recommends for an initial course. Self-pay is the norm for IV infusion and other formats, while Spravato, the FDA-approved nasal spray, is the treatment most likely to be covered by insurance, with actual coverage varying by plan.
Types of Ketamine Treatment Offered in Tennessee
IV ketamine infusion is the most widely available treatment type in Tennessee, offered across a long list of cities from the Nashville suburbs to East Tennessee. Spravato has an even broader geographic footprint and is offered in many smaller cities where IV infusion is not yet present.
Other formats such as intramuscular and oral or sublingual ketamine are available but concentrated in a smaller set of cities, mostly in the Nashville area and Knoxville. Every clinic listed here provides treatment in person.
Many clinics offer more than one format, so these figures overlap and add up to more than the total number of clinics.
- Spravato (Esketamine): 74 clinics across 28 of 33 cities in Tennessee.
- Ketamine Infusion Therapy: 27 clinics, concentrated in Knoxville, Nashville, Franklin, and Chattanooga.
- Other Ketamine Formats (intramuscular, oral, or sublingual): 10 clinics, concentrated in Nashville, Knoxville, Franklin, and Hixson.
Separately, 7 clinics in Tennessee offer Ketamine-Assisted Psychotherapy, which pairs ketamine with guided therapy sessions rather than a delivery method of its own. Concentrated in Nashville, Brentwood, Chattanooga, and Cordova.
How to Choose a Ketamine Clinic in Tennessee
Because clinics in Tennessee are spread from Memphis to the Tri-Cities, the right choice depends on where you are as much as what you need. Here are the things worth checking before you book.
- Location and travel burden: Nashville and Knoxville have the most options, but many smaller Tennessee cities have at least one clinic. Think about whether you can realistically make multiple trips, since most starter courses involve several sessions.
- Which treatment is offered: Not every clinic offers every format. IV infusion, Spravato, and other types of ketamine treatment are not always available at the same location, so confirm what a clinic provides before scheduling a consultation.
- The intake and evaluation process: A legitimate clinic will conduct a medical and psychiatric evaluation before recommending treatment. Ask how thorough that process is and whether it includes a review of your medication history.
- Clinician credentials: Find out who administers and supervises your sessions. Look for board-certified anesthesiologists, psychiatrists, or other physicians with relevant training and experience in ketamine therapy.
- Monitoring during sessions: Ask what is monitored during treatment. Blood pressure, heart rate, and your overall response should be tracked throughout each session by qualified staff on site.
- Pricing and payment options: Published pricing exists at some Tennessee clinics but not all. Ask for a full cost breakdown upfront, confirm whether your insurance covers Spravato if that is the route you are considering, and ask about payment plans.
Frequently Asked Questions
Here are answers to common questions about finding and starting ketamine therapy in Tennessee.
What conditions do Tennessee ketamine clinics typically treat?
Most clinics focus on patients who have not found relief through standard treatments. The conditions commonly addressed are treatment-resistant depression, PTSD, OCD, certain anxiety disorders, and some forms of chronic pain.
That said, ketamine therapy is not appropriate for everyone, and a licensed medical provider at the clinic will evaluate whether it makes sense for your specific situation.
How does IV ketamine infusion differ from Spravato?
IV ketamine is delivered intravenously in a clinic setting and is used off-label, meaning it is not FDA-approved for a specific psychiatric diagnosis. Spravato is an FDA-approved nasal spray containing esketamine, a related compound, and it is administered at a clinic where staff observe you for a period after each dose. The two treatments differ in delivery method, dosing schedule, and how insurance tends to handle them.
Which Tennessee cities have ketamine clinics?
The Nashville metro area, which includes Franklin, Brentwood, Murfreesboro, and surrounding suburbs, has the largest concentration of clinics. Knoxville is the main hub in East Tennessee. Cities like Chattanooga, Clarksville, Jackson, and Johnson City also have options, and Spravato in particular is offered in a wide range of smaller communities across the state.
What happens during a ketamine therapy session?
Before your first session, the clinic will conduct a medical evaluation to review your health history, current medications, and treatment goals. During the session itself, a clinician administers the treatment and monitors your blood pressure, heart rate, and overall response. Sessions typically last between 45 minutes and a few hours depending on the format, and you will need someone to drive you home afterward.
How much does ketamine therapy cost in Tennessee?
Some Tennessee clinics publish per-session pricing, which makes upfront comparison easier, though not all providers list rates publicly. The total cost for a starter course depends on which treatment you receive and how many sessions are recommended. Self-pay is standard for IV infusion, while Spravato may be covered by insurance depending on your plan and diagnosis.
Will my insurance cover ketamine therapy?
For most IV ketamine infusion, insurance coverage is uncommon and self-pay is the norm. Spravato is a different situation because it is FDA-approved and some commercial insurance plans and Medicare do cover it, though coverage terms vary widely. Call your insurer and the clinic directly to understand what is billable before committing to a course of treatment.
How do I choose the right clinic in Tennessee?
Start by confirming which treatment format the clinic offers and whether it is accessible from where you live, since most starter courses involve multiple visits. From there, ask about the intake evaluation, the credentials of the supervising clinician, what monitoring occurs during sessions, and the full cost breakdown. A clinic that answers these questions clearly and thoroughly is generally a better sign than one that keeps things vague.
Does this directory include at-home or telehealth ketamine services?
No. Every clinic listed here administers ketamine treatment in person at a physical location. At-home and telehealth ketamine services are not included in this directory.
Is ketamine therapy legal in Tennessee?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions.
Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Tennessee as it does nationwide.
The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in Tennessee and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.