Ketamine Therapy Clinics in Tennessee
37 in-person clinics across 16 cities in Tennessee.
Tennessee has developed a notably broad network of ketamine therapy providers, stretching from the Greater Nashville corridor through Chattanooga and all the way to the Tri-Cities region anchored by Johnson City. What stands out about the state is how access is not confined to a single urban hub. Smaller communities like Gallatin, Maryville, and Ooltewah have clinics as well, meaning many Tennesseans can find care within a reasonable drive.
Providers across the state work with patients dealing with treatment-resistant depression, anxiety, PTSD, chronic pain, and other conditions that have not responded well to conventional approaches. As always, a licensed medical provider is the right person to determine whether ketamine therapy is appropriate for your individual situation.
This directory covers only clinics that administer treatment on site, so every listing you find here represents a physical location where you can receive care in person.
Ketamine Clinics by City in Tennessee
Where to Find Ketamine Therapy in Tennessee
Nashville
8 clinicsNashville functions as the largest hub for ketamine therapy in Tennessee, with providers offering IV infusion, Spravato, and other modality options across the metro. The concentration of medical infrastructure in the city means patients often have multiple clinic types to compare, from psychiatry-integrated practices to dedicated infusion centers.
- Waybridge Clinics
Nashville
IV Ketamine InfusionKetamine TherapySpravato (Esketamine)TMSPsychiatryMedication Management
Franklin
5 clinicsFranklin, just south of Nashville in Williamson County, has become a meaningful destination for ketamine care in its own right, with both Spravato and broader ketamine therapy programs available locally. Residents of the southern suburbs can often access treatment here without navigating downtown Nashville traffic.
Chattanooga
4 clinicsChattanooga supports a mix of Spravato and ketamine therapy options, making it the primary access point for patients in Southeast Tennessee and the surrounding region. Its geographic position near the Georgia border also means it draws patients from communities that have fewer local options.
Brentwood
3 clinicsBrentwood sits within the Greater Nashville area and hosts providers offering both Spravato and ketamine therapy programs, giving residents of this community access to more than one treatment format. The overlap with the broader Nashville metro means patients here benefit from a competitive local landscape.
Johnson City
3 clinicsJohnson City is the standout option for Northeast Tennessee, offering all three modalities found in the state, including IV ketamine infusion, Spravato, and broader ketamine therapy approaches. For patients in the Tri-Cities area and neighboring parts of Southwest Virginia, it is often the most practical destination for specialized infusion care.
How Much Ketamine Therapy Costs in Tennessee
Across 4 clinics that publish rates, in-person sessions run $150 to $1,200 per session. A standard starter course of six sessions works out to roughly $2,130 based on the median published price. Many clinics offer package or self-pay options, so confirm current pricing directly with the provider.
Published per-infusion pricing exists for at least a handful of Tennessee clinics, which gives prospective patients a useful starting point for comparison. That said, the total cost of a care course depends on several variables: the modality chosen, the number of sessions in your initial series, the level of clinical oversight provided, and whether any preparation or integration support is included. IV ketamine infusion programs typically price differently from Spravato, because Spravato is an FDA-approved medication dispensed under a federal monitoring program and may interact with insurance benefits differently. Clinics in the Nashville corridor and Chattanooga tend to have more pricing transparency than those in smaller markets. Self-pay is the norm across most providers, so it is worth asking each clinic directly about pricing structures, package options, and any financing arrangements they work with before committing to a course of care.
Types of Ketamine Treatment Offered in Tennessee
Three main modalities are available across Tennessee. IV ketamine infusion, in which ketamine is administered directly into the bloodstream over a monitored session, is found in Nashville, Johnson City, Knoxville, and nearby communities like Hendersonville and Mount Juliet. Spravato, the FDA-approved nasal-spray form of esketamine, is the most geographically widespread option in the state, with providers in Nashville, Chattanooga, Franklin, Brentwood, Memphis, Jackson, Johnson City, Hendersonville, Mount Juliet, and Ooltewah. Spravato is only dispensed in certified healthcare settings under a federal program, so patients receive and observe the medication on site under clinical supervision. The third category, ketamine therapy delivered through intramuscular injection, sublingual formats, or ketamine-assisted psychotherapy, is available across the widest range of communities, including Memphis, Knoxville, Maryville, Clarksville, Gallatin, Bartlett, Chattanooga, Franklin, Brentwood, Nashville, Johnson City, and Mt. Juliet. This directory lists only in-person clinics, so all modalities described here involve attending a physical clinic location for each session.
- IV Ketamine Infusion offered at 5 clinics, including Hendersonville, Johnson City, Knoxville, Mount Juliet.
- Spravato (Esketamine) offered at 18 clinics, including Brentwood, Chattanooga, Franklin, Hendersonville.
- Ketamine Therapy offered at 25 clinics, including Bartlett, Brentwood, Chattanooga, Clarksville.
How to Choose a Ketamine Clinic in Tennessee
Tennessee's clinic landscape is genuinely distributed, so your first practical filter is geography. If you are in Middle Tennessee, Nashville, Franklin, and Brentwood each have multiple options and different modality mixes. If you are in East Tennessee, Johnson City covers all three modalities, while Knoxville and Maryville lean toward IV and broader therapy formats. West Tennessee patients are most likely to find options in Memphis and surrounding communities. Once you have identified clinics within a workable distance, consider these steps: confirm which modality the clinic specializes in and whether it matches your provider's recommendation, ask for itemized pricing so you can compare total course costs rather than per-session rates, verify the credentials and clinical backgrounds of the practitioners who will oversee your sessions, ask how they handle patient screening and what conditions they routinely work with, and find out what follow-up or integration support is offered after the infusion series ends. Reading patient reviews and scheduling a consultation call before committing can also help you gauge whether a clinic's approach aligns with what you are looking for.
Ketamine Therapy in Tennessee: Frequently Asked Questions
What conditions is ketamine therapy commonly used for in Tennessee clinics?
Tennessee providers generally work with patients dealing with treatment-resistant depression, major depressive disorder, anxiety disorders, PTSD, OCD, and certain chronic pain conditions. Some clinics also see patients with bipolar depression. Whether ketamine therapy is appropriate for you is a clinical determination, so speak with a licensed provider who can review your history before you pursue treatment.
What is the difference between IV ketamine infusion and Spravato?
IV ketamine infusion delivers ketamine directly into the bloodstream through an intravenous line, allowing precise dosage control over the course of each session. Spravato uses esketamine, a related compound, in a nasal-spray format. It is FDA-approved specifically for treatment-resistant depression and must be administered inside a certified clinical setting under observation for a defined monitoring period after each dose. Both are in-person treatments, but Spravato may interact with insurance coverage in ways that IV infusion typically does not, since it carries FDA approval.
Which cities in Tennessee have ketamine clinics?
Clinics are spread across the state more broadly than in many other states. Nashville, Franklin, Brentwood, Chattanooga, Johnson City, Knoxville, Memphis, Hendersonville, Mount Juliet, Ooltewah, Jackson, Clarksville, Gallatin, Maryville, Bartlett, and Maryville all have at least one provider. Use the directory to filter by city and modality to find the most current listings near you.
What does a typical ketamine infusion session involve?
Most clinics begin with an intake process that includes a medical and psychiatric evaluation to confirm you are a suitable candidate. On the day of treatment, you will be in a clinical setting with monitoring equipment in place. An IV session typically lasts between 40 minutes and an hour for the infusion itself, followed by a recovery period. You will need someone to drive you home afterward. A standard initial course usually involves multiple sessions scheduled over a few weeks, though protocols vary by clinic and patient need.
Does insurance cover ketamine therapy in Tennessee?
IV ketamine infusion is typically not covered by insurance because it is prescribed off-label, meaning it does not have FDA approval for the indications most clinics treat. Spravato is FDA-approved and is more likely to have at least partial coverage through some insurance plans, though prior authorization and specific diagnostic criteria usually apply. Most Tennessee patients pay out of pocket for IV infusion, so it is worth asking each clinic whether they offer financing, payment plans, or sliding-scale fees.
How much does a course of ketamine therapy cost in Tennessee?
Some Tennessee clinics publish their per-infusion or per-session pricing, which is helpful for initial comparison. Total costs vary depending on the modality, the number of sessions in your starting course, the clinical team involved, and whether preparation or integration support is included. The cost of Spravato also varies based on insurance involvement. Asking each clinic for a full breakdown of costs before you commit is the most reliable way to understand what you will pay.
Is ketamine therapy available outside of Nashville?
Yes. While Nashville and its southern suburbs have the highest concentration of providers, Tennessee has a notably distributed clinic landscape. Johnson City is a strong option for the Northeast corner of the state, Chattanooga serves Southeast Tennessee, and Memphis and surrounding communities cover the West. Smaller cities like Knoxville, Clarksville, and Maryville also have providers, so many Tennesseans outside Nashville are within a reasonable drive of care.
What should I look for when evaluating a clinic?
Start by confirming the qualifications of the prescribing physician and any supporting clinical staff. Look at whether the clinic conducts a thorough intake evaluation before scheduling treatment, and ask specifically how they handle patients who experience difficult responses during a session. Transparency about pricing and what is included in a care package is a good sign. Clinics that offer some form of integration support or follow-up after the initial series tend to take a more comprehensive approach to patient outcomes.
Does this directory include telehealth or at-home ketamine options?
No. Every clinic listed here administers treatment at a physical location. If you encounter a provider elsewhere that ships ketamine for home use, that falls outside the scope of this directory.
How do I decide between IV infusion and other modalities like intramuscular or sublingual ketamine?
The right modality depends on your medical history, the conditions being addressed, and the recommendation of a qualified clinician. IV infusion is the most studied delivery method and allows for precise dose adjustment. Intramuscular and sublingual formats are offered at a wider range of Tennessee clinics and may be integrated into a ketamine-assisted psychotherapy framework, where the therapeutic work done during and after the session is a core part of the protocol. Discuss the options with a provider who has reviewed your full history before choosing.
Is ketamine therapy legal in Tennessee?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions. Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Tennessee as it does nationwide. The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in Tennessee and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.