Penn Interventional Psychiatry Network

Penn Interventional Psychiatry Network offers esketamine treatment in Philadelphia, Pennsylvania for adults whose depression has not responded to adequate medication trials. Esketamine is a nasal spray approved by the FDA, sold under the brand name Spravato, and is used alongside other antidepressants.

Care starts with an evaluation by a psychiatrist who specializes in mood disorders. That visit screens for health conditions that would make the treatment unsafe. Scheduling depends on insurance approval.

Doses are given twice a week for up to four weeks, and every patient is watched for at least two hours afterward. Driving is not allowed after treatment. If symptoms improve, doses can shift to a maintenance schedule of once a week to once a month.

The program also offers TMS, ECT, and brain stimulation implants. It serves Philadelphia and the surrounding region.