Whole Systems Healthcare

Whole Systems Healthcare in Portland, Oregon offers Spravato for adults with major depressive disorder as part of an integrative approach to mental and physical wellness. The esketamine treatment is administered on site alongside both holistic and conventional options.

The clinic's naturopathic and integrative providers practice trauma-informed care, using evidence-based testing to identify root causes and building treatment plans tailored to each patient's goals. Mental health support spans natural options, medication management, and Spravato.

Beyond mental health, the practice offers hormone replacement therapy, gender-affirming care, integrative primary care, acupuncture, and genetic testing to guide medication choices. Whole Systems Healthcare is part of a larger 501(c)(3) nonprofit focused on holistic, community-centered medicine, offering both in-person and virtual appointments.