Hennessee & Associates

Hennessee & Associates in Oklahoma City offers both IV ketamine infusion and Spravato for adults with treatment-resistant depression and related conditions. The practice provides this care alongside outpatient evaluations, a Buprenorphine program, and TMS as part of comprehensive mental health treatment.

IV ketamine is administered in a clinical setting, with each infusion taking about 40 minutes and most patients undergoing nine infusions over five weeks. Some report relief after the first infusion, while many notice improvement after eight treatments, and maintenance infusions are available as needed.

Spravato, the FDA-approved esketamine nasal spray, is administered intranasally in office with at least two hours of monitoring afterward. It follows a schedule of twice weekly for the first month, then weekly, adjusted based on progress. Patients arrange a ride home on infusion days.