Cleveland Primecare

Cleveland Primecare offers Spravato (esketamine) treatment in Beachwood for adults who have tried two or more antidepressants without relief. It is also used for major depressive disorder with thoughts of self harm.

Patients spray the medication themselves at the clinic while a licensed provider supervises. Each visit runs about two hours, including checks before and after, and patients rest in a comfortable space during monitoring.

Spravato works on the NMDA receptor rather than serotonin, which is why improvement can come within hours or days instead of weeks. Dosing starts twice weekly and eases off as progress holds. The practice also provides primary care and functional medicine, and is a member of the Cleveland Clinic Quality Alliance.