Principium Psychiatry

Principium Psychiatry's Downtown Manhattan office in New York, New York, located along Wall Street and serving the Financial District, Tribeca, and SoHo, provides IV ketamine therapy and Spravato (esketamine) for treatment-resistant depression, anxiety, PTSD, and OCD. By targeting the brain's glutamate system to promote neuroplasticity, ketamine can deliver rapid relief for patients who have not responded to conventional treatments.

Treatment is administered by experienced psychiatrists through IV infusion or intranasal routes, carefully monitored in a comfortable, medically supervised environment, with Ketamine-Assisted Psychotherapy (KAP) incorporated where beneficial.

This interventional psychiatry practice also offers TMS, psychotherapy, psychopharmacology, genetic testing, and an intensive outpatient program, emphasizing personalized treatment plans and long-term support through regular follow-ups.