InnerMost

InnerMost in Manhattan, New York offers ketamine therapy and Spravato (esketamine) for depression and other mental health conditions, combining medication with therapeutic guidance to help patients process trauma, overcome entrenched patterns, and reconnect with purpose. Ketamine has been shown to reduce depressive symptoms within hours, with relief lasting up to two weeks after a single treatment, offering an option for those who have not responded to conventional antidepressants.

InnerMost views ketamine as a catalyst for change, supported by expert clinicians through a psychedelic-assisted, trauma-informed approach that blends evidence-based practice with somatic healing, breathwork, and integration.

Led by a team including a chief medical officer, physicians, and psychiatric nurse practitioners, the center offers individual and group therapy, psychotherapy, harm reduction and integration services, and access to clinical research trials. Services are provided in person and via telehealth within New York State.