Landmark Health Systems

Landmark Health Systems in Buffalo, New York is a REMS-certified Spravato center offering esketamine nasal spray, the first FDA-approved medication of its kind for adults with treatment-resistant depression who have tried two or more antidepressants. Esketamine works differently than conventional antidepressants, targeting specific brain receptors linked to mood regulation to offer rapid relief.

Administered under the careful supervision of an experienced team, Spravato often produces improvement in symptoms within hours to days. The practice combines esketamine treatment with personalized care to help patients achieve lasting wellness.

Treatment begins by determining whether Spravato is an appropriate fit, with cost support and treatment guidance provided to help patients prepare for their first session. Landmark Health Systems also offers broader psychiatric care and medication management.