Apogee Behavioral Medicine

Apogee Behavioral Medicine in Raleigh, North Carolina offers Spravato (esketamine) for adults with treatment-resistant depression and major depressive disorder with suicidal thoughts or actions. Unlike traditional oral antidepressants that target serotonin, Spravato acts on the glutamate system, often producing symptom relief within 24 hours when used alongside an oral antidepressant.

Spravato is administered under medical supervision in this REMS-certified setting, with patients self-administering the nasal spray and staying about two hours for monitoring. Treatment begins twice weekly for four weeks before tapering to maintenance dosing.

Part of a statewide network of clinics, the Raleigh office also provides TMS, psychiatry, and medication management for adults, geriatric, and pediatric patients. Apogee is in-network with most major insurers and offers same-day appointments.