Apogee Behavioral Medicine

Apogee Behavioral Medicine in Durham, North Carolina offers Spravato (esketamine) for adults with treatment-resistant depression and major depressive disorder with suicidal thoughts or actions. Spravato works differently from traditional antidepressants by acting on the brain's glutamate system, often delivering rapid relief within 24 hours when paired with an oral antidepressant.

Administered under medical supervision in a REMS-certified setting, Spravato is self-administered as a nasal spray with about two hours of monitoring afterward, starting twice weekly for four weeks before tapering to maintenance.

As part of a statewide network, the Durham office also offers TMS, psychiatry, and medication management for adults, geriatric, and pediatric patients. Apogee is in-network with most major insurance providers and offers same-day appointments.