Ketamine Therapy Clinics in Minnesota
Minnesota has a spread of ketamine therapy clinics that runs well beyond the Twin Cities metro. Providers are active in suburbs like Burnsville, Maple Grove, and Edina, and the network extends north to Duluth and west to St. Cloud. This page is a directory of in-person clinics only.
Ketamine therapy is used for conditions that have not responded well to standard treatments. Those conditions include treatment-resistant depression, PTSD, OCD, certain anxiety disorders, and some chronic pain conditions. A licensed medical provider is the right person to confirm whether it could be a good fit for a specific situation.
The sections below break down which cities have clinics, what treatment formats are available in Minnesota, and what you might expect to pay. Use the information here to shortlist options, then follow up directly with any clinic that looks promising.
Where to Find Ketamine Therapy in Minnesota
Clinics in Minnesota are spread across the Twin Cities metro and a handful of outstate cities. The heaviest concentration sits in and around Minneapolis, with additional providers in Duluth, St. Cloud, and several suburban communities.
Burnsville
3 clinicsBurnsville sits along the I-35 corridor at the southern edge of the Twin Cities, making it a natural stop for patients coming from Lakeville, Savage, Apple Valley, and communities farther south. Providers here offer Spravato, the FDA-approved nasal spray administered in a supervised clinical setting. The location keeps treatment accessible without requiring a trek into the heart of the metro.
View all 3 clinics in BurnsvilleDuluth
3 clinicsPerched above Lake Superior at the head of the Great Lakes, Duluth is the hub of northeastern Minnesota and the gateway to the Iron Range and the Northland. For residents of a region that stretches from Cloquet to the North Shore, having local access to Spravato and oral or sublingual ketamine means care that once required a long drive to the Twin Cities can now be found closer to home. The providers here serve a genuinely wide geographic footprint.
View all 3 clinics in DuluthMaple Grove
3 clinicsMaple Grove anchors the northwest Twin Cities metro, drawing patients from Plymouth, Brooklyn Park, Rogers, and the broader corridor along I-94 and Highway 169. Clinics here offer both IV infusion and Spravato, giving people in this part of the metro real options depending on what their provider recommends. The area's growth over the past two decades means strong medical infrastructure to support that range of care.
View all 3 clinics in Maple GroveMinneapolis
3 clinicsAs Minnesota's largest city, Minneapolis brings together transit access and a concentration of medical providers that few places in the state can match. Patients here can find Spravato, intramuscular ketamine, and oral or sublingual ketamine, reflecting the depth of clinical expertise the city has developed. That breadth makes Minneapolis a practical destination for patients coming in from across the broader metro, not just those who already live within city limits.
View all 3 clinics in MinneapolisEdina
2 clinicsEdina sits just southwest of Minneapolis, tucked inside the 494 loop and easy to reach from Bloomington, Eden Prairie, and the southwest suburbs. The local clinical presence is on the smaller side, with Spravato available for patients who qualify and prefer a setting close to home rather than driving into the city. Its position in the inner-ring suburbs means downtown Minneapolis is also a short trip for anyone wanting more options.
View all 2 clinics in EdinaMore Cities in Minnesota
Ketamine and Spravato providers also operate in these Minnesota cities. Select one to see local clinics, treatment formats, and how to get started.
How Much Ketamine Therapy Costs in Minnesota
Average ketamine infusion cost in Minnesota: $315 to $390 per session (based on 6 clinics with published pricing).
Several Minnesota clinics publish per-infusion pricing, which makes early comparison shopping more straightforward here than in some states. What you ultimately pay depends on which treatment format you choose and how many sessions your provider recommends for a starter course. Self-pay is the norm at most clinics, though Spravato is the format most likely to involve insurance coverage, and how much a plan covers varies considerably.
Types of Ketamine Treatment Offered in Minnesota
Spravato, the FDA-approved nasal spray, is by far the most widely available treatment format in Minnesota and is offered in cities from the Twin Cities metro out to St. Cloud and Hibbing. IV ketamine infusion is more limited and is currently found in St. Louis Park and Hibbing, while other formats like intramuscular ketamine and ketamine-assisted psychotherapy appear across a broader set of metro and outstate cities. Every clinic listed in this directory administers treatment on site.
Many clinics offer more than one format, so these figures overlap and add up to more than the total number of clinics.
- Ketamine Infusion Therapy: 6 clinics. Available in Burnsville, Eden Prairie, Hibbing, Maple Grove, and more.
- Spravato (Esketamine): 23 clinics. Available in Burnsville, Duluth, Dundas, Eden Prairie, and more.
- Other Ketamine Formats: 3 clinics. Available in Duluth, Eden Prairie, Minneapolis.Other ways ketamine is given, like intramuscular injection or oral and sublingual dosing.
Separately, 5 clinics in Minnesota offer Ketamine-Assisted Psychotherapy, which pairs ketamine with guided therapy sessions rather than a delivery method of its own. Available in Duluth, Eden Prairie, Maple Grove, Minneapolis.
How to Choose a Ketamine Clinic in Minnesota
Minnesota's clinics are spread between the Twin Cities metro and a few outstate hubs, so geography plays a real role in narrowing your options.
- Treatment format by location: Spravato is available in the widest range of cities. IV infusion is currently limited to two locations. If you have a preference, check availability before committing to a clinic.
- Intake and evaluation: Every reputable clinic starts with a medical and psychiatric evaluation before any treatment. Confirm that this step is part of the process before you book.
- Clinician credentials: Ask who will be present during sessions. Anesthesiologists, psychiatrists, and nurse practitioners all work in this space, and knowing who oversees your care is a reasonable thing to verify.
- Monitoring during sessions: A provider should be checking your blood pressure and heart rate throughout each session. Ask how the clinic handles monitoring and what their protocol is if you have a difficult reaction.
- Pricing and payment: Some Minnesota clinics publish their rates online, but not all do. Get a full cost estimate in writing before you start, and ask specifically about the number of sessions included in any quoted package.
- Follow-up care: Ketamine therapy works best when it is part of a broader treatment plan. Ask whether the clinic coordinates with your existing therapist or prescriber, or whether they offer their own integration support.
Frequently Asked Questions
Here are answers to common questions about finding and starting ketamine therapy in Minnesota.
What conditions is ketamine therapy used for in Minnesota?
Clinics in Minnesota work with patients who have treatment-resistant depression, PTSD, OCD, certain anxiety disorders, and some chronic pain conditions. These are all situations where standard treatments have not produced enough relief.
Ketamine therapy is not right for everyone. A licensed medical provider at the clinic will review your history and determine whether it is an appropriate option for you.
How does IV ketamine differ from Spravato?
IV ketamine is delivered through an intravenous line in a clinical setting and is used off-label for psychiatric conditions. Spravato is an FDA-approved nasal spray administered at a certified clinic under supervision. The two treatments use related compounds but differ in how they are given, how long a session takes, and how insurance tends to treat them.
What happens during a ketamine therapy session?
You arrive at the clinic, check in with staff, and are settled into a monitored treatment room. A clinician tracks your blood pressure and heart rate throughout the session. Sessions typically last between 45 minutes and a few hours depending on the format, and you will need someone to drive you home afterward.
Which cities in Minnesota have ketamine clinics?
The largest concentration of clinics is in and around Minneapolis, with providers also in Burnsville, Maple Grove, Edina, and other Twin Cities suburbs. Duluth is the main option for patients in northern Minnesota. Outstate cities like St. Cloud, Hibbing, and Waite Park also have providers.
Does insurance cover ketamine therapy in Minnesota?
Most ketamine therapy in Minnesota is self-pay. Spravato is the one format that some insurance plans will cover, since it carries FDA approval for treatment-resistant depression. Coverage depends entirely on the specific plan, so it is worth calling your insurer before your first appointment.
How much does ketamine therapy cost in Minnesota?
A number of Minnesota clinics post their per-infusion pricing publicly, which makes it easier to get a rough sense of costs before calling. The total cost for a starter course depends on the format chosen and the number of sessions recommended by your provider. The live price data on this page reflects what clinics in the state have published.
Do Minnesota clinics offer telehealth or at-home ketamine?
This directory lists only clinics that administer treatment on site. At-home or telehealth ketamine options are outside the scope of what is covered here.
How do I choose between clinics in the Twin Cities suburbs?
Start with the treatment format you are most likely to pursue, since IV infusion is only in a couple of locations while Spravato and other formats are more widely spread. Then compare the clinical staff credentials, what monitoring they provide, and whether their pricing is transparent. A phone call with the intake team before committing can tell you a lot about how organized and communicative a practice is.
Is ketamine therapy legal in Minnesota?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions. Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Minnesota as it does nationwide. The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in Minnesota and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.