Ketamine Therapy Clinics in Maryland

Maryland providers use ketamine therapy for several conditions that have not improved with conventional treatment. The most common are treatment-resistant depression, PTSD, and anxiety disorders, though clinicians also use it for OCD and certain chronic pain conditions.

Whether ketamine is appropriate for your situation depends on your full medical history. A licensed provider at the clinic you choose will evaluate that before recommending a course of treatment.

IV ketamine is delivered directly into the bloodstream through an infusion and is used off-label for mental health and pain conditions. Spravato is an FDA-approved nasal spray that contains esketamine, a related compound, and is self-administered in the clinic under medical supervision. The two differ in how they are given, how long sessions take, and how insurance tends to treat them.

Clinics are spread across the state, with the densest options in Baltimore, Bethesda, Rockville, Columbia, and Annapolis. Smaller cities like Frederick, Salisbury, Ellicott City, and Towson also have providers. The city list on this page shows the full breakdown by location.

Several Maryland clinics publish pricing, so some comparison shopping is possible before you call. The final cost depends on the treatment type and how many sessions make up your initial course. Self-pay is standard for IV infusions, while Spravato is more likely to be covered by insurance, though coverage depends entirely on your plan and diagnosis.

Most insurance plans do not cover IV ketamine because it is used off-label for mental health conditions. Spravato has a better chance of coverage since it is FDA-approved, but your insurer may require prior authorization or limit coverage based on diagnosis. Call your plan directly to confirm what applies to your situation.

You arrive at the clinic and a medical team reviews your condition and vital signs before the session begins. For IV infusions, you sit or recline while the medication is delivered over roughly 40 to 60 minutes.

Spravato sessions involve self-administering the nasal spray at the clinic and then staying for a monitoring period afterward. In both cases, you cannot drive yourself home.

Yes, some clinics in Maryland combine ketamine sessions with psychotherapy, particularly in Baltimore, Bethesda, Annapolis, and a few other metro-area locations. Not every clinic offers this, so ask specifically if that is something you want as part of your care.

Every clinic listed in this directory administers treatment on site at a physical location. This directory does not cover at-home or telehealth ketamine services.

Look for clinics that are transparent about their clinical team's credentials, conduct a proper medical intake before your first session, and have a clear protocol for monitoring you during treatment. A good clinic will also explain what follow-up looks like and not pressure you into committing before your questions are answered.

Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions.

Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Maryland as it does nationwide.

The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.