Guided Ascent

Guided Ascent in Johnston, Iowa offers Spravato (esketamine), an FDA-approved nasal spray for treatment-resistant depression. Administered in-clinic under medical supervision, Spravato provides relief for adults when other antidepressants have not worked.
The practice's team of mental health nurse practitioners takes a listen-first approach, drawing on personal history, past treatment, and family history to guide diagnosis and treatment planning. Guided Ascent emphasizes building a trusting therapeutic relationship and exploring alternatives beyond another medication trial.
Spravato is offered alongside psychiatric medication management, clinical genetic testing to tailor medications to a patient's genetic makeup, and an acute referral clinic providing fast-tracked evaluations. Guided Ascent is credentialed with most insurance plans and offers affordable pricing for those without coverage.
Spravato® (esketamine)
Treatment details are based on information published by the clinic, checked in August 2026.
Monday-Friday: 9:00am-4:30pm
Saturday-Sunday: Closed
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