Principium Psychiatry

Principium Psychiatry in Greenwich, Connecticut offers IV ketamine therapy and Spravato (esketamine) for treatment-resistant depression, anxiety, PTSD, OCD, and other conditions that have not responded to traditional treatments. Ketamine works by targeting the brain's glutamate system and NMDA receptors to promote neuroplasticity, often producing relief within hours or days.

Administered by highly trained psychiatrists, treatment is personalized through IV infusion or intranasal routes and closely monitored in a serene, medically supervised setting, with Ketamine-Assisted Psychotherapy (KAP) integrated where appropriate.

A physician-led interventional psychiatry practice, the Greenwich office also provides TMS, psychotherapy, psychopharmacology, and genetic testing, with care coordinated seamlessly across Principium's locations through shared records and treatment protocols.