Ketamine Therapy Clinics in Colorado
92 in-person clinics across 32 cities in Colorado.
Colorado has developed one of the more geographically broad ketamine therapy landscapes in the Mountain West. While Denver anchors the largest concentration of providers, clinics have taken root from the Western Slope cities of Grand Junction and Durango all the way through the Front Range corridor to Fort Collins and Loveland. That spread means many Coloradans can find in-person care without a long drive to the capital.
The treatment options available here reflect the full current range of ketamine modalities. IV infusion remains the most widely offered approach, but Spravato, the FDA-approved esketamine nasal spray, is accessible in a solid number of Front Range communities, and integrative options such as ketamine-assisted psychotherapy and intramuscular or sublingual formats are offered across both urban centers and smaller mountain-adjacent towns.
Whether you are exploring this therapy for depression, anxiety-related conditions, PTSD, or chronic pain, the providers listed here administer treatment on site at their clinics. A licensed medical provider should guide your decision about which approach is appropriate for your situation.
Ketamine Clinics by City in Colorado
Arvada
2 clinics
Aspen
1 clinic
Aurora
4 clinics
Boulder
9 clinics
Broomfield
3 clinics
Centennial
3 clinics
Colorado Springs
10 clinics
Denver
17 clinics
Durango
2 clinics
Edwards
1 clinic
Englewood
4 clinics
Fort Collins
4 clinics
Frisco
1 clinic
Glenwood Springs
1 clinic
Grand Junction
3 clinics
Greeley
1 clinic
Greenwood Village
3 clinics
Highlands Ranch
1 clinic
Lafayette
1 clinic
Lakewood
3 clinics
Littleton
3 clinics
Longmont
2 clinics
Louisville
1 clinic
Loveland
1 clinic
Montrose
1 clinic
Monument
1 clinic
Parker
3 clinics
Superior
1 clinic
Thornton
1 clinic
Westminster
2 clinics
Wheatridge
1 clinic
Wheat Ridge
1 clinic
Where to Find Ketamine Therapy in Colorado
Denver
17 clinicsDenver is the state's primary hub for ketamine therapy, with providers offering IV infusions, Spravato, and integrative ketamine-assisted psychotherapy across the metro. The density of clinics here gives patients the widest choice of settings, provider backgrounds, and treatment formats. Many of Colorado's most established practices are concentrated in and immediately around the city.
- Denver Wellness Associates
Denver
IV Ketamine InfusionSpravato (Esketamine)PsychiatryMedication Management - LifeStance Health
Denver
IV Ketamine InfusionSpravato (Esketamine)PsychiatryMedication ManagementTherapy
Colorado Springs
10 clinicsColorado Springs supports a meaningful cluster of clinics serving the southern Front Range, with all three major modalities present, including IV infusion, Spravato, and broader ketamine therapy formats. For residents between Denver and Pueblo, it functions as the most accessible regional hub. The city's military and veteran population has also driven demand for trauma-focused mental health care.
Boulder
9 clinicsBoulder's clinic scene leans toward integrative approaches, with ketamine-assisted psychotherapy options available alongside IV infusion. The city's broader culture of wellness and mental health awareness has supported providers who pair clinical ketamine treatment with therapeutic preparation and integration work. Nearby communities such as Lafayette, Superior, and Louisville also host practices serving the Boulder County area.
Aurora
4 clinicsAurora offers strong access to all three modalities, making it one of the more comprehensively served cities in the metro area. Its position on the eastern edge of Denver means residents have both local options and easy reach into the broader Denver provider network. Clinics here cover IV infusion, Spravato, and integrative ketamine therapy formats.
- LifeStance Health
Aurora
IV Ketamine InfusionSpravato (Esketamine)PsychiatryMedication ManagementTherapy
Englewood
4 clinicsEnglewood sits in the southern Denver metro and hosts providers offering IV ketamine infusion and ketamine-assisted psychotherapy. Its proximity to Littleton, Centennial, and Greenwood Village, all of which also have clinics, means the immediate area forms one of the denser suburban pockets for treatment access on the south side of metro Denver.
- Ballen Medical & Wellness
Englewood
IV Ketamine InfusionKetamine TherapyPsychiatryMedication Management
How Much Ketamine Therapy Costs in Colorado
Across 11 clinics that publish rates, in-person sessions run $285 to $1,375 per session. A standard starter course of six sessions works out to roughly $2,400 based on the median published price. Many clinics offer package or self-pay options, so confirm current pricing directly with the provider.
Colorado is one of the states where published per-infusion pricing exists for a meaningful share of clinics, giving prospective patients a reasonable basis for comparison before calling. Costs vary based on several factors: the modality chosen, with IV infusion and Spravato programs priced differently; the length and complexity of each session; whether psychological integration support is bundled in; and the overhead of the practice setting, which tends to differ between a downtown Denver clinic and a smaller community provider in a mountain town. A standard starter course of IV infusions, typically a series of six sessions, generally runs in the low-to-mid thousands of dollars when priced at the clinic level. Self-pay is the norm for IV ketamine since most commercial insurance does not cover it as an off-label treatment. Spravato occupies a different position because it is FDA-approved for certain diagnoses and some insurance plans do cover it, though coverage varies by plan and diagnosis. It is always worth confirming directly with both the clinic and your insurer before assuming coverage applies.
Types of Ketamine Treatment Offered in Colorado
Three main modalities are represented across Colorado's clinic directory. IV ketamine infusion is the most widely distributed, found not only across the Denver metro suburbs like Lakewood, Littleton, Centennial, and Westminster but also in communities well outside the Front Range, including Durango, Aspen, Frisco, and Grand Junction. This geographic reach is relatively uncommon compared to most states. Spravato, the FDA-approved esketamine nasal spray administered in a supervised clinical setting, is concentrated along the Front Range from Fort Collins and Loveland south through the Denver suburbs and into Colorado Springs, with Western Slope access in Grand Junction as well. Integrative ketamine therapy formats, which include intramuscular administration, sublingual dosing, and ketamine-assisted psychotherapy, show the widest geographic footprint of any modality, appearing in cities from Greeley and Longmont in the north to Montrose and Glenwood Springs in the west, and in suburban communities such as Arvada, Highlands Ranch, Thornton, and Longmont. This directory covers only in-person clinics where treatment is administered on site by qualified clinical staff.
- IV Ketamine Infusion offered at 33 clinics, including Aspen, Aurora, Broomfield, Centennial.
- Spravato (Esketamine) offered at 35 clinics, including Aurora, Broomfield, Centennial, Colorado Springs.
- Ketamine Therapy offered at 63 clinics, including Arvada, Aspen, Aurora, Boulder.
How to Choose a Ketamine Clinic in Colorado
Because Colorado's clinics are spread across a large and varied geography, your starting point should be location and travel practicality. Front Range residents have the most options and can reasonably compare several providers, while those in mountain communities or on the Western Slope may have one or two local options and should verify what is available before planning a longer trip. Once you have identified reachable clinics, consider these questions: Does the clinic offer the specific modality your provider has recommended, or are you open to discussing which format suits your situation? Is psychological integration support included, or would you need to arrange that separately? Does the clinic publish pricing transparently, and if so, does the per-session cost fit within a budget you can sustain for a full course? For Spravato, does the clinic work with your insurance, and have they confirmed your specific plan's coverage? What are the medical director's credentials and the clinical team's experience with the conditions you are seeking to address? Finally, how does the clinic handle follow-up care and communicate with your existing mental health or primary care providers? Taking time to ask these questions before booking will help you find a setting where you feel both clinically supported and comfortable.
Ketamine Therapy in Colorado: Frequently Asked Questions
What conditions is ketamine therapy most commonly used for in Colorado clinics?
Clinics across Colorado most frequently offer ketamine therapy for treatment-resistant depression, major depressive disorder, anxiety disorders, PTSD, obsessive-compulsive disorder, and certain chronic pain conditions. Some integrative practices with ketamine-assisted psychotherapy also work with patients on trauma processing and general psychological wellbeing. Always consult a licensed medical provider to determine whether ketamine therapy is appropriate for your specific diagnosis and history.
What is the difference between IV ketamine infusion and Spravato?
IV ketamine infusion delivers racemic ketamine directly into the bloodstream through an intravenous line in a supervised clinical setting. It is used off-label, meaning it is not formally FDA-approved for psychiatric indications, and as a result it is rarely covered by insurance. Spravato is an FDA-approved nasal spray containing esketamine, a closely related compound, that is self-administered by the patient under clinical supervision in the office. Because it carries FDA approval for specific diagnoses, some insurance plans cover it, though not universally. Both require you to remain at the clinic for a monitored observation period after dosing.
Which cities in Colorado have the most ketamine clinic options?
Denver has the largest concentration of providers in the state, with multiple clinics offering all three major modalities. Colorado Springs is the main hub for the southern Front Range. Boulder, Aurora, Englewood, Greenwood Village, Littleton, and Centennial form a dense suburban ring around Denver with strong access. Outside the metro, Grand Junction stands out as the best-served Western Slope city, and communities like Durango, Fort Collins, and Loveland have solid options as well.
What does a typical ketamine infusion visit involve?
Before your first infusion, a clinic will typically conduct a medical intake to review your health history, current medications, and mental health background. On the day of treatment, an IV line is placed and the infusion runs over roughly 40 to 60 minutes, though timing varies by clinic and protocol. You will remain in a monitored room throughout. Most clinics recommend bringing an eye mask and music to help with the experience. You will need someone to drive you home afterward. A full initial course usually involves multiple sessions scheduled over two to three weeks.
Does insurance cover ketamine therapy in Colorado?
For IV ketamine infusion, insurance coverage is uncommon because it is used off-label. Most patients pay out of pocket. Spravato has a better chance of coverage because it carries FDA approval for certain diagnoses, but coverage still depends heavily on your specific insurance plan, your diagnosis, and whether you have met prior-authorization requirements. It is worth calling your insurer directly and asking the clinic whether they have experience navigating coverage for your plan before you commit to a treatment path.
How much does ketamine therapy cost in Colorado?
Colorado is one of the states where a meaningful number of clinics publish their per-infusion pricing, so comparison is more straightforward here than in states where pricing is not disclosed. A starter course of IV ketamine infusions, typically a series of six sessions, generally falls in the low-to-mid thousands of dollars in total. Individual session pricing and package rates vary by clinic, modality, and whether integration support is included. The exact figures rendered on each clinic's listing reflect publicly available information at the time of our last update.
What is ketamine-assisted psychotherapy and where is it available in Colorado?
Ketamine-assisted psychotherapy, often abbreviated KAP, pairs a ketamine dosing session with structured psychotherapeutic work, typically including a preparation session before dosing and an integration session afterward to help process the experience. It is often delivered using intramuscular or sublingual ketamine rather than IV infusion. This format is available in Boulder, Denver, Colorado Springs, and a wide range of other communities across the state, including some smaller cities and mountain towns.
Can I do ketamine therapy remotely or at home?
This directory lists only clinics that administer ketamine treatment in person at a supervised clinical facility. At-home or telehealth ketamine services are not included here, and patients should discuss any remote options separately with a licensed provider who can advise on safety and appropriateness.
How do I find a ketamine clinic near me if I live outside Denver?
Colorado's clinic landscape extends well beyond the metro, so residents in many parts of the state have local options worth exploring first. The directory lets you browse by city, so searching your nearest town or the closest larger community is a practical starting point. Grand Junction, Durango, Fort Collins, Loveland, and Glenwood Springs all have providers, and suburban communities like Parker, Broomfield, Westminster, and Arvada are also covered. If no clinic is close to home, Denver and Colorado Springs together have the broadest selection for those willing to travel.
How should I prepare for my first consultation at a ketamine clinic?
Most clinics ask you to bring a list of your current medications, particularly any psychiatric medications, since some can interact with ketamine or affect its efficacy. Having records or a letter from your referring psychiatrist or therapist can speed up the intake process. Think in advance about your treatment goals and be prepared to discuss your diagnosis history honestly. Ask the clinic directly about what to expect during and after a session, what their follow-up protocol looks like, and whether they coordinate with outside mental health providers.
Is ketamine therapy legal in Colorado?
Yes. Ketamine is a Schedule III controlled substance under U.S. federal law and is legal for licensed clinicians to prescribe and administer off-label, including for treatment-resistant depression and other conditions. Spravato (esketamine), the FDA-approved nasal-spray form, is dispensed only in certified healthcare settings under a federal Risk Evaluation and Mitigation Strategy (REMS) program. That applies in Colorado as it does nationwide. The standards for who may administer treatment are set by state regulators and by the clinicians themselves; you can look up the current licensing board for your state through the Federation of State Medical Boards directory at fsmb.org. This page is informational and not legal or medical advice. Consult a licensed medical provider before starting treatment.
This directory provides information about in-person ketamine therapy clinics in Colorado and does not endorse any provider or offer medical advice. Ketamine therapy is used for certain conditions but is not appropriate for everyone. Always consult a licensed medical professional to determine whether treatment is right for you.