Acacia Clinics

Acacia Clinics in Sunnyvale, California offers Spravato (esketamine), a prescription nasal spray for adults with major depressive disorder who have not found relief with other antidepressants. Containing esketamine, it targets the brain's NMDA receptor to help restore synaptic connections involved in mood regulation, working through a different pathway than conventional antidepressants and sometimes providing relief within hours or days.

Treatment begins with an initial consultation to determine if Spravato is appropriate. The first dose is administered in-clinic with about two hours of monitoring, and most patients continue twice weekly for the first month, then weekly or every two weeks thereafter.

Acacia added Spravato to complement its TMS and accelerated TMS programs, providing another pathway for patients who have not responded to other treatments. The clinic accepts most insurance plans and offers private pay and financial aid options.