Principium Psychiatry

Principium Psychiatry in Santa Monica, California serves patients throughout Los Angeles, Brentwood, and Beverly Hills, offering IV ketamine therapy and Spravato (esketamine) for treatment-resistant depression, anxiety, PTSD, and OCD. Ketamine targets the brain's glutamate system to promote neuroplasticity, providing rapid relief for those who have not found success with conventional antidepressants or psychotherapy.
Treatment is delivered by trained psychiatrists through IV infusion or intranasal routes, carefully monitored in a comfortable, medically supervised environment, with Ketamine-Assisted Psychotherapy (KAP) incorporated where appropriate.
This interventional psychiatry practice also provides TMS, Spravato, psychotherapy, and comprehensive medication management, with personalized, long-term care plans and the same clinical standards maintained across all Principium locations.
IV Ketamine Infusions
Offered by this practiceSpravato® (esketamine)
Offered by this practiceUsed for:
Treatment details are based on information published by the clinic, checked in August 2026.
Monday to Friday 9am to 8pm
Weekends by appointment
Contact clinic for pricing.
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