Amast Health

Amast Health in San Francisco, California offers Spravato (esketamine) through a psychedelic-assisted therapy model that pairs the FDA-approved nasal spray with structured talk therapy and behavioral change rather than relying on medication alone. The clinic treats Spravato as a catalyst that opens a window for change through symptom relief and neuroplasticity, with patients self-administering in-clinic, monitored for two hours, then going home the same day.

The therapy draws on multiple modalities including the Montreal Model of ketamine therapy, ACT, CBT, DBT, mindfulness, and psychodynamic approaches, with care personalized around each patient's values and goals. Most insurance covers Spravato for treatment-resistant depression. The clinic serves San Francisco and the surrounding Bay Area communities.